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These are the Fugates, also known as The Blue People of Kentucky, they are  carriers of a rare genetic trait that causes the disease methemoglobinemia,  which causes bluing of the skin :
These are the Fugates, also known as The Blue People of Kentucky, they are carriers of a rare genetic trait that causes the disease methemoglobinemia, which causes bluing of the skin :

The Fugate Family of Kentucky Had Blue Skin For Generations
The Fugate Family of Kentucky Had Blue Skin For Generations

DNA suggests 10,000-year-old Brit had dark skin, blue eyes | CBC News
DNA suggests 10,000-year-old Brit had dark skin, blue eyes | CBC News

Well-intended Appalachia-set drama 'Blue' fails to gel - Los Angeles Times
Well-intended Appalachia-set drama 'Blue' fails to gel - Los Angeles Times

8 Astonishing Facts About the Blue Fugates
8 Astonishing Facts About the Blue Fugates

Incestuous family were so inbred their skin turned BLUE and was passed down  generations - Mirror Online
Incestuous family were so inbred their skin turned BLUE and was passed down generations - Mirror Online

Real-life 'Blue Man' dies after heart attack, stroke
Real-life 'Blue Man' dies after heart attack, stroke

The True Story of the Blue People of Kentucky | HowStuffWorks
The True Story of the Blue People of Kentucky | HowStuffWorks

Argyria - Wikipedia
Argyria - Wikipedia

Pin on curiouser and curiouser
Pin on curiouser and curiouser

A family of people with blue skin lived in Kentucky for many generations.  The Fulgates of
A family of people with blue skin lived in Kentucky for many generations. The Fulgates of

Almost Blu
Almost Blu

Man who turned blue after taking silver for skin condition dies – New York  Daily News
Man who turned blue after taking silver for skin condition dies – New York Daily News

Paul Karason - Wikipedia
Paul Karason - Wikipedia

The Blue-Skinned People Of Kentucky: Their Stories And The Ridiculous  Troubles That They Have To Face: Novel About Prejudice by Jarod Branstetter  | Goodreads
The Blue-Skinned People Of Kentucky: Their Stories And The Ridiculous Troubles That They Have To Face: Novel About Prejudice by Jarod Branstetter | Goodreads

Man turned completely blue after taking dietary supplements for years
Man turned completely blue after taking dietary supplements for years

JCM | Free Full-Text | Clinical and Forensic Aspects of the Different  Subtypes of Argyria
JCM | Free Full-Text | Clinical and Forensic Aspects of the Different Subtypes of Argyria

Blue man syndrome | CMAJ
Blue man syndrome | CMAJ

Meet The Fugate Family, The Mysterious Blue People Of Kentucky
Meet The Fugate Family, The Mysterious Blue People Of Kentucky

8 Astonishing Facts About the Blue Fugates
8 Astonishing Facts About the Blue Fugates

Why this man's skin turned blue
Why this man's skin turned blue

8 Astonishing Facts About the Blue Fugates
8 Astonishing Facts About the Blue Fugates

Blue Fugates: A Family Of People Whose Skin Was Actually Blue
Blue Fugates: A Family Of People Whose Skin Was Actually Blue

The man who turned blue after taking a dietary supplement for years
The man who turned blue after taking a dietary supplement for years

Incestuous family 'so inbred' their skin turned blue from genetic condition  - Daily Record
Incestuous family 'so inbred' their skin turned blue from genetic condition - Daily Record

The real life Papa Smurf: Man turned himself BLUE after taking dietary  supplements for years | Daily Mail Online
The real life Papa Smurf: Man turned himself BLUE after taking dietary supplements for years | Daily Mail Online

The Tragic Reason Why One Man Actually Turned Blue Forever / Bright Side
The Tragic Reason Why One Man Actually Turned Blue Forever / Bright Side